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Article

Mesocortical Dopamine Phenotypes in Mice Lacking the Sonic Hedgehog Receptor Cdon.

eNeuro - 1 Jan 2000

Verwey Michael, Grant Alanna, Meti Nicholas, Adye-White Lauren, Torres-Berrío Angelica, Rioux Veronique, Lévesque Martin, Charron Frederic, Flores Cecilia

Abstract excerpt

Motivated behaviors and many psychopathologies typically involve changes in dopamine release from the projections of the ventral tegmental area (VTA) and/or the substantia nigra pars compacta (SNc). The morphogen Sonic Hedgehog (Shh) specifies fates of midbrain dopamine neurons, but VTA-specific effects of Shh signaling are also being uncovered. In this study, we assessed the role of the Shh receptor Cdon in the...

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Identifiers

PMID: 27419218
DOI: 10.1523/ENEURO.0009-16.2016
PMCID: PMC4942720

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