Article
Integrating multiple oestrogen receptor alpha ChIP studies: overlap with disease susceptibility regions, DNase I hypersensitivity peaks and gene expression.
BMC medical genomics - 30 Oct 2013
Handel Adam E, Sandve Geir K, Disanto Giulio, Handunnetthi Lahiru, Giovannoni Gavin, Ramagopalan Sreeram V
Abstract excerpt
BACKGROUND: A wealth of nuclear receptor binding data has been generated by the application of chromatin immunoprecipitation (ChIP) techniques. However, there have been relatively few attempts to apply these datasets to human complex disease or traits. METHODS: We integrated multiple oestrogen receptor alpha (ESR1) ChIP datasets in the Genomic Hyperbrowser. We analysed these datasets for overlap with DNase I...
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