Article

EstroGene database reveals diverse temporal, context-dependent and directional estrogen receptor regulomes in breast cancer

2023-02-02

Abstract excerpt

As one of the most successful cancer therapeutic targets, estrogen receptor-α (ER/ESR1) has been extensively studied in decade-long. Sequencing technological advances have enabled genome-wide analysis of ER action. However, reproducibility is limited by different experimental design. Here, we established the EstroGene database through centralizing 246 experiments from 136 transcriptomic, cistromic and epigenetic d...

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Literature Corpus work: e3724137-33dd-5dbc-835a-904b4d235800
DOI: 10.1101/2023.01.30.526388

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