Article

Deciphering ESR1-driven transcription in human endometrial stromal cells via transcriptome, cistrome, and integration with chromatin landscape

2025-04-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> To investigate ESR1 and estrogen-driven transcription in human endometrial stromal cells. <h4>Design</h4> Telomerase-immortalized human endometrial stromal cells were engineered to activate ESR1 using the CRISPR activation system and treated with vehicle or E2. Primary endometrial stromal cells were treated with vehicle or decidualization cocktail. <h4>Subjects</h4> Biopsie...

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Literature Corpus work: e1c49ea2-b147-5b49-b2b4-24cee6b79e08
DOI: 10.1101/2025.04.23.650343

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