Article

Discovering human transcription factor interactions with genetic variants, novel DNA motifs, and repetitive elements using enhanced yeast one-hybrid assays

2018-11-01

Abstract excerpt

<h4>ABSTRACT</h4> Identifying transcription factor (TF) binding to noncoding variants, uncharacterized DNA motifs, and repetitive genomic elements has been technically and computationally challenging. Current experimental methods, such as chromatin immunoprecipitation, generally test one TF at a time, and computational motif algorithms often lead to false positive and negative predictions. To address these limita...

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Literature Corpus work: 40bec120-b0e2-5c9e-9a24-0b13077d3a47
DOI: 10.1101/459305

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