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Article

Hypermutability and error catastrophe due to defects in ribonucleotide reductase.

Proceedings of the National Academy of Sciences of the United States of America - 12 Nov 2013

Ahluwalia Deepti, Schaaper Roel M

Abstract excerpt

The enzyme ribonucleotide reductase (RNR) plays a critical role in the production of deoxynucleoside-5'-triphosphates (dNTPs), the building blocks for DNA synthesis and replication. The levels of the cellular dNTPs are tightly controlled, in large part through allosteric control of RNR. One impor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24167285
DOI: 10.1073/pnas.1310849110
PMCID: PMC3832021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24167285-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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