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Article

Longest neurite-specific activation of Rap1B in hippocampal neurons contributes to polarity formation through RalA and Nore1A in addition to PI3-kinase.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Nov 2013

Nakamura Takeshi, Yasuda Sayaka, Nagai Hiroyuki, Koinuma Shingo, Morishita So, Goto Akihiro, Kinashi Tatsuo, Wada Naoyuki

Abstract excerpt

In a developing nervous system, axon-dendrite formation is instructed by extrinsic cues, and the mechanism whereby a developing neuron interprets these cues using intracellular signaling is particularly important. Studies using dissociated hippocampal neurons have identified many signaling pathways underlying neuronal polarization. Among the components of these pathways, Rap1B is essential for axon specification...

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Source

Identifiers

PMID: 24165023
DOI: 10.1111/gtc.12097

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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