Article
Polarity-regulating kinase partitioning-defective 1/microtubule affinity-regulating kinase 2 negatively regulates development of dendrites on hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 28 Nov 2007
Terabayashi Takeshi, Itoh Tomohiko J, Yamaguchi Hideki, Yoshimura Yuta, Funato Yosuke, Ohno Shigeo, Miki Hiroaki
Abstract excerpt
Neurons are highly polarized cells that possess two morphologically and functionally different types of protrusions, axons and dendrites, that function in the transmission and reception of neural signals, respectively. A great deal of attention has been paid to the specification and guidance of axons, but the mechanism of dendrite development remains mostly unknown. We report here that a polarity-regulating...
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