Article
Neurite extension in central neurons: a novel role for the receptor tyrosine kinases Ror1 and Ror2.
Journal of cell science - 15 Jan 2005
Paganoni Sabrina, Ferreira Adriana
Abstract excerpt
Neurite elongation and branching are key cellular events during brain development as they underlie the formation of a properly wired neuronal network. Here we report that the receptor tyrosine kinases Ror1 and Ror2 modulate the growth of neurites as well as their branching pattern in hippocampal neurons. Upon Ror1 or Ror2 suppression using antisense oligonucleotides or RNA interference (RNAi), neurons extended...
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