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Article

PtdIns (3,4,5) P3 recruitment of Myo10 is essential for axon development.

PloS one - 1 Jan 2012

Yu Huali, Wang Nannan, Ju Xingda, Yang Yan, Sun Dong, Lai Mingming, Cui Lei, Sheikh Muhammad Abid, Zhang Jianhua, Wang Xingzhi, Zhu Xiaojuan

Abstract excerpt

Myosin X (Myo10) with pleckstrin homology (PH) domains is a motor protein acting in filopodium initiation and extension. However, its potential role has not been fully understood, especially in neuronal development. In the present study the preferential accumulation of Myo10 in axon tips has been revealed in primary culture of hippocampal neurons with the aid of immunofluorescence from anti-Myo10 antibody in...

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Identifiers

PMID: 22590642
DOI: 10.1371/journal.pone.0036988
PMCID: PMC3349655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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