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Article

RalA and the exocyst complex influence neuronal polarity through PAR-3 and aPKC.

Journal of cell science - 15 May 2009

Lalli Giovanna

Abstract excerpt

Neuronal polarization requires localized cytoskeletal changes and polarized membrane traffic. Here, I report that the small GTPase RalA, previously shown to control neurite branching, also regulates neuronal polarity. RalA depletion, or ectopic expression of constitutively active RalA in cultured neurons inhibit axon formation. However, expression of a constitutively active RalA mutant that is unable to interact...

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Identifiers

PMID: 19383721
DOI: 10.1242/jcs.044339

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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