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Article

A novel approach to tracking antigen-experienced CD4 T cells into functional compartments via tandem deep and shallow TCR clonotyping.

Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 2013

Estorninho Megan, Gibson Vivienne B, Kronenberg-Versteeg Deborah, Liu Yuk-Fun, Ni Chester, Cerosaletti Karen, Peakman Mark

Abstract excerpt

Extensive diversity in the human repertoire of TCRs for Ag is both a cornerstone of effective adaptive immunity that enables host protection against a multiplicity of pathogens and a weakness that gives rise to potential pathological self-reactivity. The complexity arising from diversity makes detection and tracking of single Ag-specific CD4 T cells (ASTs) involved in these immune responses challenging. We report...

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Source

Identifiers

PMID: 24163407
DOI: 10.4049/jimmunol.1300622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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