Article
Association between polymorphisms in the csrRS two-component regulatory system and invasive group A streptococcal infection.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 May 2014
Lin J-N, Chang L-L, Lai C-H, Lin H-H, Chen Y-H
Abstract excerpt
The csrRS two-component regulatory system is an important element in the pathogenesis of group A Streptococcus (GAS). The main goal of this study is to understand the association between csrRS polymorphisms and GAS infection. We sequenced the csrRS genes from 172 clinical isolates, including 81 invasive and 91 noninvasive isolates, and then employed phylogenetic analyses to determine the consequences of the csrRS...
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