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Identification of Group A Streptococcus Genes Directly Regulated by CsrRS and Novel Intermediate Regulators

13 Jul 2021

Abstract excerpt

Group A Streptococcus (GAS) is an important public health threat as a cause of sore throat, skin infections, life-threatening invasive infections, and the postinfectious complications of acute rheumatic fever, a leading cause of acquired heart disease. This work characterizes CsrRS, a GAS system for the detection of environmental signals that enables adaptation of the bacteria for survival in the human throat by...

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PMID: 34253064
DOI: 10.1128/mbio.01642-21

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