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Variation in the Group BStreptococcusCsrRS Regulon and Effects on Pathogenicity

19 Jan 2008

Abstract excerpt

CsrRS (or CovRS) is a two-component regulatory system that controls expression of multiple virulence factors in the important human pathogen group B Streptococcus (GBS). We now report global gene expression studies in GBS strains 2603V/R and 515 and their isogenic csrR and csrS mutants. Together with data reported previously for strain NEM316, the results reveal a conserved 39-gene CsrRS regulon. In vitro...

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PMID: 18203834
DOI: 10.1128/jb.01677-07

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