Article
Molecular reclassification of Crohn's disease: a cautionary note on population stratification.
PloS one - 1 Jan 2013
Maus Bärbel, Jung Camille, Mahachie John Jestinah M, Hugot Jean-Pierre, Génin Emmanuelle, Van Steen Kristel
Abstract excerpt
Complex human diseases commonly differ in their phenotypic characteristics, e.g., Crohn's disease (CD) patients are heterogeneous with regard to disease location and disease extent. The genetic susceptibility to Crohn's disease is widely acknowledged and has been demonstrated by identification of over 100 CD associated genetic loci. However, relating CD subphenotypes to disease susceptible loci has proven to be a...
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