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Article

Robust methods for population stratification in genome wide association studies

19 Apr 2013

Abstract excerpt

BACKGROUND: Genome-wide association studies can provide novel insights into diseases of interest, as well as to the responsiveness of an individual to specific treatments. In such studies, it is very important to correct for population stratification, which refers to allele frequency differences between cases and controls due to systematic ancestry differences. Population stratification can cause spurious...

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PMID: 23601181
DOI: 10.1186/1471-2105-14-132

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