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Article

Risk categorization for complex disorders according to genotype relative risk and precision in parameter estimates.

Genetic epidemiology - 1 Sept 2010

Goddard Graham H M, Lewis Cathryn M

Abstract excerpt

PURPOSE: To develop a method of genetic risk categorization based on the risk conferred by genetic variants and the precision with which risks are known. METHODS: We develop a method for risk assignment based on an "average" member of the population and their genotype, deriving empirical confidence intervals encompassing all relevant sources of variation in disease risk. An individual with risk confidence...

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PMID: 20568294
DOI: 10.1002/gepi.20519

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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