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Article

Molecular reclassification of Crohn's disease by cluster analysis of genetic variants.

PloS one - 23 Sept 2010

Cleynen Isabelle, Mahachie John Jestinah M, Henckaerts Liesbet, Van Moerkercke Wouter, Rutgeerts Paul, Van Steen Kristel, Vermeire Severine

Abstract excerpt

BACKGROUND: Crohn's Disease (CD) has a heterogeneous presentation, and is typically classified according to extent and location of disease. The genetic susceptibility to CD is well known and genome-wide association scans (GWAS) and meta-analysis thereof have identified over 30 susceptibility loci. Except for the association between ileal CD and NOD2 mutations, efforts in trying to link CD genetics to clinical...

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Identifiers

PMID: 20886065
DOI: 10.1371/journal.pone.0012952
PMCID: PMC2944846

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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