Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single Nucleotide Polymorphism Clustering in Systemic Autoimmune Diseases.

PloS one - 1 Jan 2016

Charlon Thomas, Martínez-Bueno Manuel, Bossini-Castillo Lara, Carmona F David, Di Cara Alessandro, Wojcik Jérôme, Voloshynovskiy Sviatoslav, Martín Javier, Alarcón-Riquelme Marta E

Abstract excerpt

Systemic Autoimmune Diseases, a group of chronic inflammatory conditions, have variable symptoms and difficult diagnosis. In order to reclassify them based on genetic markers rather than clinical criteria, we performed clustering of Single Nucleotide Polymorphisms. However naive approaches tend to group patients primarily by their geographic origin. To reduce this "ancestry signal", we developed SNPClust, a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Databases, Genetic
Share to HLA Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Human Genome Project

Share to Lupus Erythematosus, Systemic

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 27490238
DOI: 10.1371/journal.pone.0160270
PMCID: PMC4973908

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single Nucleotide Polymorphism Clustering in Systemic Autoimmune Diseases.PMID 27490238Read ↗

A phenotypic and genomics approach in a multi-ethnic cohort to subtype systemic lupus erythematosusSemantic proximity Read ↗

Analysis and application of European genetic substructure using 300 K SNP information.Semantic proximity Read ↗

Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune DiseasesSemantic proximity Read ↗

Genome-Wide Association Analysis Reveals Genetic Heterogeneity of Sjögren's Syndrome According to Ancestry.Semantic proximity Read ↗

A genome-wide admixture scan for ancestry-linked genes predisposing to sarcoidosis in African-Americans.Semantic proximity Read ↗

Cluster analysis of clinical manifestations assigns systemic lupus erythematosus-phenotype subgroups: A multicentre study on 440 patients.Semantic proximity Read ↗

Genetic ancestry, serum interferon-α activity, and autoantibodies in systemic lupus erythematosus.Semantic proximity Read ↗

Efficient population assignment and outlier detection in human populations using biallelic markers chosen by principal component-based rankings.Semantic proximity Read ↗

Sparse principal component analysis for identifying ancestry-informative markers in genome-wide association studies.Semantic proximity Read ↗

An unsupervised machine learning method for discovering patient clusters based on genetic signatures.Semantic proximity Read ↗

Response to anti-IL17 therapy in inflammatory disease is not strongly impacted by genetic background.Semantic proximity Read ↗

Molecular reclassification of Crohn's disease: a cautionary note on population stratification.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.