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Article

Continuous and widespread roles for the Swi-Snf complex in transcription.

The EMBO journal - 15 Apr 1999

Biggar S R, Crabtree G R

Abstract excerpt

Chromatin presents a significant obstacle to transcription, but two means of overcoming its repressive effects, histone acetylation and the activities of the Swi-Snf complex, have been proposed. Histone acetylation and Swi-Snf activity have been shown to be crucial for transcriptional induction and to facilitate binding of transcription factors to DNA. By regulating the activity of the Swi-Snf complex in vivo, we...

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Identifiers

PMID: 10205178
DOI: 10.1093/emboj/18.8.2254
PMCID: PMC1171308

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Continuous and widespread roles for the Swi-Snf complex in transcription.PMID 10205178Read ↗

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