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Article

NLRP3 polymorphisms are associated with late-onset Alzheimer's disease in Han Chinese.

Journal of neuroimmunology - 15 Dec 2013

Tan Meng-Shan, Yu Jin-Tai, Jiang Teng, Zhu Xi-Chen, Wang Hui-Fu, Zhang Wei, Wang Ying-Li, Jiang Wei, Tan Lan

Abstract excerpt

The innate immunity and inflammatory response plays an important role in AD pathogenesis. Recently, a wealth of information linking the activation of NLRP3 inflammasome to Alzheimer's disease (AD) pathogenesis has emerged. Considering the pivotal role of NLRP3 in the inflammatory process and in AD, we hypothesized that variations in NLRP3 gene may also affect susceptibility to AD. Three selected functional...

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Source

Identifiers

PMID: 24144834
DOI: 10.1016/j.jneuroim.2013.10.002

Genes

NLRP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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