Article
Single nucleotide polymorphism rs1333049 on chromosome 9p21.3 is associated with Alzheimer's disease in Han Chinese.
Clinica chimica acta; international journal of clinical chemistry - 6 Sept 2010
Yu Jin-Tai, Yu Yang, Zhang Wei, Wu Zhong-Chen, Li Yang, Zhang Na, Tan Lan
Abstract excerpt
BACKGROUND: Chromosome 9p21.3 polymorphism has been shown to affect susceptibility to Alzheimer's disease (AD) in Caucasians, while there are no studies on the association of chromosome 9p21.3 polymorphism with the risk of AD in Asians. METHODS: The study investigated 266 sporadic late-onset AD (LOAD) and 323 healthy controls matched for sex and age in a Han Chinese population. The common genetic variant (tagged...
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