Article
INPP5D rs35349669 polymorphism with late-onset Alzheimer's disease: A replication study and meta-analysis.
Oncotarget - 25 Oct 2016
Jing Hua, Zhu Jun-Xia, Wang Hui-Fu, Zhang Wei, Zheng Zhan-Jie, Kong Ling-Li, Tan Chen-Chen, Wang Zi-Xuan, Tan Lin, Tan Lan
Abstract excerpt
Inositol polyphosphate-5-phosphatase (INPP5D) was reported to be associated with Alzheimer's disease (AD) through modulating the inflammatory process and immune response. A recent genome-wide association study discovered a new locus single nucleotide polymorphism (SNP, rs35349669) of INPP5D which was significantly associated with susceptibility to late-onset Alzheimer's disease (LOAD) in Caucasians. In this...
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