Article

The association of NLRP3 polymorphisms and its downstream interaction in mild cognitive impairment

2025-03-23

Abstract excerpt

<h4>Background</h4> Nucleotide-binding domain and leucine-rich repeat (LRR)-containing family protein 3 (NLRP3) has been widely studied in the pathogenesis of mild cognitive impairments (MCI) and Alzheimer’s Disease (AD). Single nucleotide polymorphisms (SNPs) of NLRP3 gene are associated with various diseases, however the association between NLRP3 SNPs and downstream pathway is unclear. <h4>Methods</h4> 12 intron...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cadaf62a-254d-51f2-a5ff-bd2ec013d5d7
DOI: 10.1101/2025.03.21.25324400

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The association of NLRP3 polymorphisms and its downstream interaction in mild cognitive impairmentDOI 10.1101/2025.03.21.25324400Read

Functional significance of NLRP3 polymorphisms in mild cognitive impairment.Semantic proximity Read

NLRP3 polymorphisms are associated with late-onset Alzheimer's disease in Han Chinese.Semantic proximity Read

A Polymorphism Within the 3'UTR of NLRP3 is Associated with Susceptibility for Ischemic Stroke in Chinese Population.Semantic proximity Read

Circulating long noncodingRNAs in Mild Cognitive Impairment patients’ bloodSemantic proximity Read

The Association of Calcium Signaling Pathway Gene Variants, Bone Mineral Density and Mild Cognitive Impairment in Elderly People.Semantic proximity Read

The 3'UTR Polymorphisms in the NLRP3 Gene Associated with the Risk of COPD and Their Putative Effects on the microRNA Mechanism.Semantic proximity Read

Common Variant in PLD3 Influencing Cerebrospinal Fluid Total Tau Levels and Hippocampal Volumes in Mild Cognitive Impairment Patients from the ADNI Cohort.Semantic proximity Read

The 3’-UTR Polymorphisms in the NLRP3 Gene Associated with the Risk of COPD and Their Putative Effects on the microRNA MechanismSemantic proximity Read

Human Leukocyte Antigen and microRNAs as Key Orchestrators of Mild Cognitive Impairment and Alzheimer's Disease: A Systematic Review.Semantic proximity Read

The Association between Polymorphism of NLRP3 rs10754558 and Susceptibility to Arteriosclerosis Obliterans in Chinese Han Male PopulationSemantic proximity Read

Variants in NLRP3 and NLRC4 inflammasome associate with susceptibility and severity of multiple sclerosisSemantic proximity Read

CHI3L1 drives astrocyte-medicated neuronal injury via GAL3-NLRP3 signaling in ischemic strokeSemantic proximity Read