Article
A polymorphism linked to RRAS, SCAF1, IRF3 and BCL2L12 genes is associated with cirrhosis in hepatitis C virus carriers.
Liver international : official journal of the International Association for the Study of the Liver - 1 Apr 2014
Real Luis M, Caruz Antonio, Rivero-Juarez Antonio, Soriano Vicente, Neukam Karin, Rivero Antonio, Cifuentes Celia, Mira José A, Macías Juan, Pineda Juan A
Abstract excerpt
BACKGROUND & AIMS: Host genetic factors could play a primary role in determining risk for cirrhosis development in HCV-infected patients. The aims of this study were to discover new genetic variants associated with this trait and to replicate some associations formerly reported. METHODS: Three hundred and thirty-seven HCV carriers with available data about liver fibrosis status, who initiated treatment with...
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