Article
A polymorphism linked to RRAS, SCAF1, IRF3 and BCL2L12 genes is associated with cirrhosis in hepatitis C virus carriers.
Liver international : official journal of the International Association for the Study of the Liver - 1 Apr 2014
Real Luis M, Caruz Antonio, Rivero-Juarez Antonio, Soriano Vicente, Neukam Karin, Rivero Antonio, Cifuentes Celia, Mira José A, Macías Juan, Pineda Juan A
Abstract excerpt
BACKGROUND & AIMS: Host genetic factors could play a primary role in determining risk for cirrhosis development in HCV-infected patients. The aims of this study were to discover new genetic variants associated with this trait and to replicate some associations formerly reported. METHODS: Three hu...
Topics
- Carrier State
- Genotype
- Hepatitis C
- Humans
- Interferon Regulatory Factor-3
- Interferon-alpha
- Interferons
- Interleukins
- Liver Cirrhosis
- Logistic Models
- Muscle Proteins
- Odds Ratio
- Polyethylene Glycols