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Article

Risk Factors for Hepatocellular Carcinoma in Cirrhotic Patients with Chronic Hepatitis B.

Genetic testing and molecular biomarkers - 1 Sept 2016

Zhang Yuan-Qing, Peng Li-Jun, Cao Yi-Rong, Zeng Zhi-Ping, Wu Yu-Jing, Shi Hong, Cheng Shi-Yao, Wang Ji-Yao, Friedman Scott L, Sninsky John J, Guo Jin-Sheng

Abstract excerpt

AIMS: To investigate the clinical and genetic risk factors associated with hepatocellular carcinoma (HCC) in cirrhotic patients with chronic hepatitis B (CHB). METHODS: Nine hundred forty-nine Chinese Han patients with CHB were studied, including noncirrhotic patients without HCC (N = 234), cirrhotic patients without (N = 281) and with HCC (N = 434). Patients were genotyped for 10 candidate single nucleotide...

Topics

Adult
Aged
Carcinoma, Hepatocellular
Female
Hepatitis B virus
Hepatitis B, Chronic
Humans
Liver Cirrhosis
Liver Neoplasms
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Odds Ratio

Polymorphism, Single Nucleotide

Risk Factors

Source

Identifiers

PMID: 27391584
DOI: 10.1089/gtmb.2016.0062

Genes

TLR4
MLEC
SOCS3
SPP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-27391584-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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