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Article

PNPLA3 and IL 28B signature for predicting susceptibility to chronic hepatitis C infection and fibrosis progression.

Archives of physiology and biochemistry - 1 Apr 2022

Youssef Samar Samir, Abbas Eman Abd El Razek, Youness Rana Ahmed, Elemeery Moustafa Nouh, Nasr Amal Soliman, Seif Sameh

Abstract excerpt

BACKGROUND: Association studies identified genetic polymorphisms as predictive risk factors of rapid fibrosis progression in chronic hepatitis C (CHC). This study aims to assess the impact of IL28B rs8099917 polymorphism on CHC genotype 4 (G4) susceptibility and liver fibrosis progression individually; and in combination with PNPLA3 rs738409. PATIENTS AND METHODS: IL28B rs8099917 and PNPLA3 rs738409 were...

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Identifiers

PMID: 31793339
DOI: 10.1080/13813455.2019.1694039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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