Article
Impact of IL12B gene rs 3212227 polymorphism on fibrosis, liver inflammation, and response to treatment in genotype 4 Egyptian hepatitis C patients.
Disease markers - 1 Jan 2013
Youssef Samar Samir, Mostafa Asmaa, Saad Amr, Omran Moataza Hassan, El Zanaty Taher, Mohamed Seif Sameh
Abstract excerpt
INTRODUCTION: Hepatitis C virus (HCV) infection affects almost 3% of the world's population with the highest prevalence in Egypt (15%). The standard therapy; pegylated interferon (PEG-IFN) and ribavirin, is effective in only 60% of Egyptian patients; moreover it is costly, prolonged, and has severe side effects, so prediction of response is essential to reduce burden of unfavorable treatment. Several viral and...
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