Article
A 7 gene signature identifies the risk of developing cirrhosis in patients with chronic hepatitis C.
Hepatology (Baltimore, Md.) - 1 Aug 2007
Huang Hongjin, Shiffman Mitchell L, Friedman Scott, Venkatesh Ramasubbu, Bzowej Natalie, Abar Olivia T, Rowland Charles M, Catanese Joseph J, Leong Diane U, Sninsky John J, Layden Thomas J, Wright Teresa L, White Thomas, Cheung Ramsey C
Abstract excerpt
UNLABELLED: Clinical factors such as age, gender, alcohol use, and age-at-infection influence the progression to cirrhosis but cannot accurately predict the risk of developing cirrhosis in patients with chronic hepatitis C (CHC). The aim of this study was to develop a predictive signature for cirrhosis in Caucasian patients. All patients had well-characterized liver histology and clinical factors; DNA was...
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