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Article

Genome-wide methylation profiling of ADPKD identified epigenetically regulated genes associated with renal cyst development.

Human genetics - 1 Mar 2014

Woo Yu Mi, Bae Jae-Bum, Oh Yeon-Hee, Lee Young-Gun, Lee Min Joo, Park Eun Young, Choi Jung-Kyoon, Lee Sunyoung, Shin Yubin, Lyu Jaemyun, Jung Hye-Yoon, Lee Yeon-Su, Hwang Young-Hwan, Kim Young-Joon, Park Jong Hoon

Abstract excerpt

Autosomal dominant polycystic kidney disease (ADPKD) is a common human genetic disease characterized by the formation of multiple fluid-filled cysts in bilateral kidneys. Although mutations in polycystic kidney disease 1 (PKD1) are predominantly responsible for ADPKD, the focal and sporadic property of individual cystogenesis suggests another molecular mechanism such as epigenetic alterations. To determine the...

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PMID: 24129831
DOI: 10.1007/s00439-013-1378-0

Genes

PKD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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