Systems biology approaches toward autosomal dominant polycystic kidney disease (ADPKD)

Abstract excerpt

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD), a common of monogenetic disorder caused by the polycystic kidney disease-1 (PKD1) or PKD2 genes deficiency. In this study, we have re-analyzed a microarray dataset to generate a holistic view of this disease. METHODOLOGY: GSE7869, an expression profiling dataset was downloaded from the Gene Expression Omnibus (GEO) database. After quality control...

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