The murine T-cell receptor uses a limited repertoire of expressed V beta gene segments.

doi:10.1038/316517a0

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Article

The murine T-cell receptor uses a limited repertoire of expressed V beta gene segments.

Nature - 1 Jan 2000

Barth R K, Kim B S, Lan N C, Hunkapiller T, Sobieck N, Winoto A, Gershenfeld H, Okada C, Hansburg D, Weissman I L

Abstract excerpt

Only 10 different V beta gene segments were found when the sequences of 15 variable (V beta) genes of the mouse T-cell receptor were examined. From this analysis we calculate that the total number of expressed V beta gene segments may be 21 or fewer, which makes the expressed germline V beta repe...

Topics

Amino Acid Sequence
Animals
Epitopes
Gene Expression Regulation
Genes
Macromolecular Substances
Major Histocompatibility Complex
Mice
Mutation
Receptors, Antigen, T-Cell
Recombination, Genetic
T-Lymphocytes

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Open in PubMed

Identifiers

PMID: 2412120
DOI: 10.1038/316517a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2412120-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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