Article
Analysis of sheep T-cell receptor beta-chain heterogeneity.
Immunogenetics - 1 Mar 1999
Halsey W A, Palmer B E, DeMartini J C, Howell M D
Abstract excerpt
We analyzed nucleotide and deduced amino acid sequence heterogeneity of sheep T-cell receptor beta-chain cDNAs isolated from an anchored-polymerase chain reaction library. Evaluation of 34 individual rearrangements has defined 18 new beta-chain variable region sequences which have been clustered...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- Consensus Sequence
- DNA, Complementary
- Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
- Genes, T-Cell Receptor beta
- Genetic Variation
- Germ Cells
- Humans
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Receptors, Antigen, T-Cell, alpha-beta
- Sequence Alignment
- Sequence Analysis, DNA