Article
Structure and diversity of T-lymphocyte antigen receptors alpha and gamma in Xenopus.
Immunogenetics - 1 Sept 2002
Haire Robert N, Kitzan Haindfield Melanie K, Turpen James B, Litman Gary W
Abstract excerpt
Short primer PCR directed at conserved regions of amino acid sequence within the T-cell antigen receptor (TCR) and immunoglobulin (Ig) light chain variable ( V) regions was used to amplify putative TCRgamma V region amplicons from stage 45 Xenopus laevis (African clawed frog) mRNA (cDNA). An adult Xenopus spleen cDNA library was screened using the Vgamma and a putative TCRValpha amplicon. Full copy length cDNAs...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA, Complementary
- Evolution, Molecular
- Genetic Variation
- Models, Genetic
- Molecular Sequence Data
- Phylogeny
- Polymerase Chain Reaction
- RNA, Messenger
- Receptors, Antigen, T-Cell, alpha-beta
- Receptors, Antigen, T-Cell, gamma-delta
- Sequence Homology, Amino Acid
- Xenopus laevis