Article
Dominant expression of a distinctive V14+ T-cell antigen receptor alpha chain in mice.
Proceedings of the National Academy of Sciences of the United States of America - 1 Sept 1991
Koseki H, Asano H, Inaba T, Miyashita N, Moriwaki K, Lindahl K F, Mizutani Y, Imai K, Taniguchi M
Abstract excerpt
A distinctive variable region 14-positive (V14+) alpha chain (V alpha 14+) of the T-cell antigen receptor is predominantly expressed in multiple mouse subspecies. The V alpha 14 family has two members, V alpha 14.1 and V alpha 14.2, which differ by only three amino acids at positions 50-52. Based on the EcoRI restriction fragment length polymorphism of the gene encoding V alpha 14, mice can be divided into three...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Southern
- DNA
- Gene Expression
- Gene Frequency
- Genes, Dominant
- Genetic Variation
- Macromolecular Substances
- Mice