Article
Oligoclonal bands and age at onset correlate with genetic risk score in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 May 2014
Harbo Hanne F, Isobe Noriko, Berg-Hansen Pål, Bos Steffan D, Caillier Stacy J, Gustavsen Marte W, Mero Inger-Lise, Celius Elisabeth Gulowsen, Hauser Stephen L, Oksenberg Jorge R, Gourraud Pierre-Antoine
Abstract excerpt
BACKGROUND: Many genetic risk variants are now well established in multiple sclerosis (MS), but the impact on clinical phenotypes is unclear. OBJECTIVE: To investigate the impact of established MS genetic risk variants on MS phenotypes, in well-characterized MS cohorts. METHODS: Norwegian MS patients (n = 639) and healthy controls (n = 530) were successfully genotyped for 61 established MS-associated single...
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