Article
Genetics for understanding and predicting clinical progression in multiple sclerosis.
Revue neurologique - 1 Nov 2011
Depaz R, Granger B, Cournu-Rebeix I, Bouafia A, Fontaine B
Abstract excerpt
INTRODUCTION: Multiple sclerosis (MS) is a dys-immune disease of the central nervous system with highly variable and unpredictable long-term outcome. STATE OF THE ART: In the early 1970s association between HLA alleles and MS was established. Very recently, the power of Genome Wide Association Studies (GWAS) enabled the identification of several loci involved in immune functions as genetic risk factors in MS....
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