Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles.

doi:10.1371/journal.pone.0058352

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Article

Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles.

PloS one - 1 Jan 2013

Mero Inger-Lise, Gustavsen Marte W, Sæther Hanne S, Flåm Siri T, Berg-Hansen Pål, Søndergaard Helle B, Jensen Poul Erik H, Berge Tone, Bjølgerud Anja, Muggerud Aslaug, Aarseth Jan H, Myhr Kjell-Morten, Celius Elisabeth G, Sellebjerg Finn, Hillert Jan, Alfredsson Lars, Olsson Tomas, Oturai Annette Bang, Kockum Ingrid, Lie Benedicte A, Andreassen Bettina Kulle, Harbo Hanne F

Abstract excerpt

The presence of oligoclonal bands (OCB) in cerebrospinal fluid (CSF) is a typical finding in multiple sclerosis (MS). We applied data from Norwegian, Swedish and Danish (i.e. Scandinavian) MS patients from a genome-wide association study (GWAS) to search for genetic differences in MS relating to OCB status. GWAS data was compared in 1367 OCB positive and 161 OCB negative Scandinavian MS patients, and nine of the...

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PMID: 23472185
DOI: 10.1371/journal.pone.0058352
PMCID: PMC3589422

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