Genetic burden of common variants in progressive and bout-onset multiple sclerosis.

doi:10.1177/1352458513512707

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Article

Genetic burden of common variants in progressive and bout-onset multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Jun 2014

Sorosina Melissa, Brambilla Paola, Clarelli Ferdinando, Barizzone Nadia, Lupoli Sara, Guaschino Clara, Osiceanu Ana Maria, Moiola Lucia, Ghezzi Angelo, Coniglio Gabriella, Patti Francesco, Mancardi Gianluigi, Manunta Paolo, Glorioso Nicola, Guerini Franca R, Bergamaschi Roberto, Perla Franco, Martinelli Vittorio, Cusi Daniele, Leone Maurizio, Comi Giancarlo, D'Alfonso Sandra, Martinelli-Boneschi Filippo

Abstract excerpt

BACKGROUND: The contribution of genetic variants underlying the susceptibility to different clinical courses of multiple sclerosis (MS) is still unclear. OBJECTIVE: The aim of the study is to evaluate and compare the proportion of liability explained by common SNPs and the genetic burden of MS-associated SNPs in progressive onset (PrMS) and bout-onset (BOMS) cases. METHODS: We estimated the proportion of variance...

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PMID: 24277324
DOI: 10.1177/1352458513512707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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