Article
A new allele of the lpr locus, lprcg, that complements the gld gene in induction of lymphadenopathy in the mouse.
The Journal of experimental medicine - 1 Feb 1990
Matsuzawa A, Moriyama T, Kaneko T, Tanaka M, Kimura M, Ikeda H, Katagiri T
Abstract excerpt
Several mice with generalized lymphadenopathy were found in the CBA/KlJms (CBA) colony maintained at our institute. A new mutant strain of mice that develop massive lymphoid hyperplasia at 100% incidence within 5 mo after birth was established by crossing these diseased mice. Genetic studies on l...
Topics
- Alleles
- Animals
- Chromosome Mapping
- DNA
- Female
- Flow Cytometry
- Fluorescent Antibody Technique
- Hyperplasia
- Immunoglobulins
- Lymph Nodes
- Lymphatic Diseases
- Male
- Mice
- Mice, Inbred Strains
- Mutation
- Organ Size
- Spleen