Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genotype-restricted lymphoproliferation in autoimmune lpr mice.

European journal of immunology - 1 Jun 1991

Matsuzawa A, Kimura M, Muraiso T, Kominami R, Katagiri T

Abstract excerpt

Transfer of bone marrow (BM) from autoimmunity-prone mice homozygous for the new lymphoproliferation mutation (lprcg) caused systemic lymphoproliferation in irradiated lprcg/lprcg recipients but not in irradiated +/+ recipient (J. Exp. Med. 1990. 171:519; Eur. J. Immunol. 1991.21: 63). It was thus hypothesized that the lprcg gene expresses its function at lymph nodes (LN) to provide anomalous lprcg/lprcg lymphoid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune Diseases
Share to Bone Marrow Transplantation
Share to Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lymph Nodes

Share to Lymphoproliferative Disorders

Share to Mice, Inbred C3H

Share to Mice, Inbred CBA

Source

Identifiers

PMID: 2044659
DOI: 10.1002/eji.1830210630

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genotype-restricted lymphoproliferation in autoimmune lpr mice.PMID 2044659Read ↗

Lymphadenopathy induced by the cooperation between lprcg and gld genes is of lpr but not of gld phenotype.Semantic proximity Read ↗

Autoimmunity in mice bearing lprcg: a novel mutant gene.Semantic proximity Read ↗

A new allele of the lpr locus, lprcg, that complements the gld gene in induction of lymphadenopathy in the mouse.Semantic proximity Read ↗

The Yaa mutation induces the development of autoimmunity in mice heterozygous for the gld (generalized lymphadenopathy disease) mutation.Semantic proximity Read ↗

Bone marrow transplantation from mutant lpr/lpr mice. Functional abnormalities rather than alloantigenic differences appear to determine the development of a graft-vs.-host-like syndrome.Semantic proximity Read ↗

Distinctive expression of lprcg in the heterozygous state on different genetic backgrounds.Semantic proximity Read ↗

Tetraparental mice reveal complex cellular interactions of the mutant, autoimmunity-inducing lpr gene.Semantic proximity Read ↗

Transgenic T cell receptor interactions in the lymphoproliferative and autoimmune syndromes of lpr and gld mutant mice.Semantic proximity Read ↗

<i>Lpr</i> and <i>gld</i>: Single Gene Models of Systemic Autoimmunity and Lymphoproliferative DiseaseSemantic proximity Read ↗

lpr And gld: Single Gene Models Of Systemic Autoimmunity And Lymphoproliferative DiseaseSemantic proximity Read ↗

Functional analyses of lpr gene in MRL/Mp-lpr/lpr mice. Role of lymph node stromal cells in lpr-lymphadenopathy.Semantic proximity Read ↗

Novel origin of lpr and gld cells and possible implications in autoimmunity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.