Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autoregulation of PurR repressor synthesis and involvement of purR in the regulation of purB, purC, purL, purMN and guaBA expression in Escherichia coli.

European journal of biochemistry - 26 Jan 1990

Meng L M, Kilstrup M, Nygaard P

Abstract excerpt

The purR gene encodes a repressor (PurR) controlling the synthesis of the enzymes of purine biosynthesis. The subunit of PurR was identified as a 38-kDa polypeptide by SDS/polyacrylamide gel electrophoresis. Analysis of a purR-lacZ transcriptional fusion indicated that purR expression is autoregulated. This was confirmed by gel retardation and DNaseI footprinting experiments, where two PurR-binding sites were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Binding Sites
Share to DNA

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Genes, Bacterial

Share to Molecular Sequence Data

Share to Mutation

Share to Plasmids

Source

Identifiers

PMID: 2404765
DOI: 10.1111/j.1432-1033.1990.tb15314.x

Genes

SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autoregulation of PurR repressor synthesis and involvement of purR in the regulation of purB, purC, purL, purMN and guaBA expression in Escherichia coli.PMID 2404765Read ↗

Genes of the Escherichia coli pur regulon are negatively controlled by a repressor-operator interaction.Semantic proximity Read ↗

Regulation of the Escherichia coli glyA gene by the purR gene product.Semantic proximity Read ↗

Identification of hypoxanthine and guanine as the co-repressors for the purine regulon genes of Escherichia coli.Semantic proximity Read ↗

Regulation of Escherichia coli pyrC by the purine regulon repressor protein.Semantic proximity Read ↗

In vivo effect of mutations at the PRPP binding site of the Bacillus subtilis purine repressor.Semantic proximity Read ↗

Mutational analysis of the Bacillus subtilis purA operator site.Semantic proximity Read ↗

Mutations in PurBox1 of the Bacillus subtilis pur operon control site affect adenine-regulated expression in vivo.Semantic proximity Read ↗

Definition of a second Bacillus subtilis pur regulon comprising the pur and xpt-pbuX operons plus pbuG, nupG (yxjA), and pbuE (ydhL).Semantic proximity Read ↗

Mutations in the Bacillus subtilis purine repressor that perturb PRPP effector function in vitro and in vivo.Semantic proximity Read ↗

The nucleotide messenger (p)ppGpp is a co-repressor of the purine synthesis transcription regulator PurR in FirmicutesSemantic proximity Read ↗

Role of the purine repressor in the regulation of pyrimidine gene expression in Escherichia coli K-12.Semantic proximity Read ↗

RutR is the uracil/thymine-sensing master regulator of a set of genes for synthesis and degradation of pyrimidines.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.