Article
Autoregulation of PurR repressor synthesis and involvement of purR in the regulation of purB, purC, purL, purMN and guaBA expression in Escherichia coli.
European journal of biochemistry - 26 Jan 1990
Meng L M, Kilstrup M, Nygaard P
Abstract excerpt
The purR gene encodes a repressor (PurR) controlling the synthesis of the enzymes of purine biosynthesis. The subunit of PurR was identified as a 38-kDa polypeptide by SDS/polyacrylamide gel electrophoresis. Analysis of a purR-lacZ transcriptional fusion indicated that purR expression is autoregu...
Topics
- Base Sequence
- Binding Sites
- DNA
- Electrophoresis, Polyacrylamide Gel
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Molecular Sequence Data
- Mutation
- Operator Regions, Genetic
- Plasmids
- Purines
- Repressor Proteins
- Transcription Factors