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Article

Genes of the Escherichia coli pur regulon are negatively controlled by a repressor-operator interaction.

Journal of bacteriology - 1 Aug 1990

He B, Shiau A, Choi K Y, Zalkin H, Smith J M

Abstract excerpt

Fusions of lacZ were constructed to genes in each of the loci involved in de novo synthesis of IMP. The expression of each pur-lacZ fusion was determined in isogenic purR and purR+ strains. These measurements indicated 5- to 17-fold coregulation of genes purF, purHD, purC, purMN, purL, and purEK and thus confirm the existence of a pur regulon. Gene purB, which encodes an enzyme involved in synthesis of IMP and in...

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Identifiers

PMID: 2198266
DOI: 10.1128/jb.172.8.4555-4562.1990
PMCID: PMC213288

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Genes of the Escherichia coli pur regulon are negatively controlled by a repressor-operator interaction.PMID 2198266Read ↗

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