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Article

RutR is the uracil/thymine-sensing master regulator of a set of genes for synthesis and degradation of pyrimidines.

Molecular microbiology - 1 Nov 2007

Shimada Tomohiro, Hirao Kiyo, Kori Ayako, Yamamoto Kaneyoshi, Ishihama Akira

Abstract excerpt

Using the genomic SELEX, a total of six Escherichia coli DNA fragments have been identified, which formed complexes with transcription factor RutR. The RutR regulon was found to include a large number of genes encoding components for not only degradation of pyrimidines but also transport of glutamate, synthesis of glutamine, synthesis of pyrimidine nucleotides and arginine, and degradation of purines. DNase I...

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Identifiers

PMID: 17919280
DOI: 10.1111/j.1365-2958.2007.05954.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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