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Article

Regulation of Escherichia coli pyrC by the purine regulon repressor protein.

Journal of bacteriology - 1 Jun 1990

Choi K Y, Zalkin H

Abstract excerpt

The purine regulon repressor, PurR, was identified as a component of the Escherichia coli regulatory system for pyrC, the gene that encodes dihydroorotase, an enzyme in de novo pyrimidine nucleotide synthesis. PurR binds to a pyrC control site that resembles a pur regulon operator and represses expression by twofold. Mutations that increase binding of PurR to the control site in vitro concomitantly increase in...

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Identifiers

PMID: 1971620
DOI: 10.1128/jb.172.6.3201-3207.1990
PMCID: PMC209125

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Regulation of Escherichia coli pyrC by the purine regulon repressor protein.PMID 1971620Read ↗

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