Article
Role of the purine repressor in the regulation of pyrimidine gene expression in Escherichia coli K-12.
Journal of bacteriology - 1 Jun 1990
Wilson H R, Turnbough C L
Abstract excerpt
The pyrC and pyrD genes of Escherichia coli K-12 encode the pyrimidine biosynthetic enzymes dihydroorotase and dihydroorotate dehydrogenase, respectively. A highly conserved sequence in the promoter regions of these two genes is similar to the pur operator, which is the binding site for the purin...
Topics
- Amidohydrolases
- Base Sequence
- Dihydroorotase
- Dihydroorotate Oxidase
- Escherichia coli
- Gene Expression Regulation, Enzymologic
- Molecular Sequence Data
- Mutation
- Oxidoreductases
- Purines
- Pyrimidine Nucleotides
- Pyrimidines
- Repressor Proteins
- Transcription Factors
