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Article

Role of the purine repressor in the regulation of pyrimidine gene expression in Escherichia coli K-12.

Journal of bacteriology - 1 Jun 1990

Wilson H R, Turnbough C L

Abstract excerpt

The pyrC and pyrD genes of Escherichia coli K-12 encode the pyrimidine biosynthetic enzymes dihydroorotase and dihydroorotate dehydrogenase, respectively. A highly conserved sequence in the promoter regions of these two genes is similar to the pur operator, which is the binding site for the purine repressor (PurR). In this study, we examined the role of PurR in the regulation of pyrC and pyrD expression. Our...

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Identifiers

PMID: 1971621
DOI: 10.1128/jb.172.6.3208-3213.1990
PMCID: PMC209126

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Related research

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Role of the purine repressor in the regulation of pyrimidine gene expression in Escherichia coli K-12.PMID 1971621Read ↗

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Genetic evidence that promoter P2 is the physiologically significant promoter for the pyrBI operon of Escherichia coli K-12.Semantic proximity Read ↗

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In vivo effect of mutations at the PRPP binding site of the Bacillus subtilis purine repressor.Semantic proximity Read ↗

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Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.Semantic proximity Read ↗

Cloning, sequencing, and characterizing the Lactobacillus leichmannii pyrC gene encoding dihydroorotase.Semantic proximity Read ↗

Definition of a second Bacillus subtilis pur regulon comprising the pur and xpt-pbuX operons plus pbuG, nupG (yxjA), and pbuE (ydhL).Semantic proximity Read ↗

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