Article
Regulation of the Escherichia coli glyA gene by the purR gene product.
Journal of bacteriology - 1 Jul 1990
Steiert J G, Rolfes R J, Zalkin H, Stauffer G V
Abstract excerpt
The purine regulon repressor protein, PurR, was shown to be a purine component involved in glyA regulation in Escherichia coli. Expression of glyA, encoding serine hydroxymethyltransferase activity, was elevated in a purR mutant compared with a wild-type strain. When the purR mutant was transformed with a plasmid carrying the purR gene, the serine hydroxymethyltransferase levels returned to the wild-type level....
Topics
- Base Sequence
- Binding Sites
- DNA, Bacterial
- Deoxyribonuclease I
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Glycine
- Glycine Hydroxymethyltransferase
- Molecular Sequence Data
- Mutation