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Article

Role of key residues of obelin in coelenterazine binding and conversion into 2-hydroperoxy adduct.

Journal of photochemistry and photobiology. B, Biology - 5 Oct 2013

Eremeeva Elena V, Markova Svetlana V, van Berkel Willem J H, Vysotski Eugene S

Abstract excerpt

Bioluminescence of a variety of marine organisms is caused by monomeric Ca(2+)-regulated photoproteins, to which a peroxy-substituted coelenterazine, 2-hydroperoxycoelenterazine, is firmly bound. From the spatial structure the side chains of Tyr138, His175, Trp179, and Tyr190 of obelin are situated within the substrate-binding pocket at hydrogen bond distances with different atoms of the...

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Identifiers

PMID: 24041851
DOI: 10.1016/j.jphotobiol.2013.08.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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