Article
Hyperactive Arg39Lys mutated mnemiopsin: implication of positively charged residue in chromophore binding cavity.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology - 1 Apr 2015
Mahdavi Atiyeh, Sajedi Reza H, Hosseinkhani Saman, Taghdir Majid
Abstract excerpt
Mnemiopsin, a Ca(2+)-regulated photoprotein isolated from Mnemiopsis leidyi, belongs to the family of ctenophore photoproteins. These proteins emit blue light from a chromophore, which is tightly but non-covalently bound in their central hydrophobic core that contains 21 conserved residues. In an effort to investigate the role of Arg39 (the sole charged residue in coelenterazine binding cavity of ctenophore...
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